Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
Hi Doctors, I Went To A Breast Cancer Conference And
Question: Hi Doctors, I went to a breast cancer conference and the medical oncologist talked about how Tamoxifen has gone from 5 years to 10 years trending towards 15 years. Also stated Evista might be better because it doesn’t cause as much uterine CA (assuming woman still has her uterus) or osteoporosis. I’m 10 years out from double lumpectomies and still have my uterus and ovaries. And I’m BRACA gene 1 and 2 negative. What’s your opinion on staying on a selective estrogen receptor modulator after 10 years? Thank you very much, Kim
Brief Answer:
Hello. as of now there is no data
Detailed Answer:
Hello XXXXXXX Welcome to HCM. I understand your concern being a brave cancer survivor.
So definitely, extended tamoxifen offers advantage in terms of preventing a relapse. As of now , we have data for 10 years but at the marginally increased cost of carcinoma endometrium. Anastrazole and letrozole are better in this regard as the side effect profile is better. After 10 years, theoretically speaking , more tamoxifen and anastrazole/letrozole should offer more protection . But then medicine is based on evidences and we dont have a fifteen year data now. Sooner the evidence is there, it will get incorporated into guidelines. There is no harm , but i will advise anastrazole/letrozole as compared to tamoxifen for you.
Thanks and regards
Hello. as of now there is no data
Detailed Answer:
Hello XXXXXXX Welcome to HCM. I understand your concern being a brave cancer survivor.
So definitely, extended tamoxifen offers advantage in terms of preventing a relapse. As of now , we have data for 10 years but at the marginally increased cost of carcinoma endometrium. Anastrazole and letrozole are better in this regard as the side effect profile is better. After 10 years, theoretically speaking , more tamoxifen and anastrazole/letrozole should offer more protection . But then medicine is based on evidences and we dont have a fifteen year data now. Sooner the evidence is there, it will get incorporated into guidelines. There is no harm , but i will advise anastrazole/letrozole as compared to tamoxifen for you.
Thanks and regards
Above answer was peer-reviewed by :
Dr. Remy Koshy
What is the difference/and or advantage between Evista and Anastrozole/letrozole?
Brief Answer:
Hello. raloxifene(evista) is less effective
Detailed Answer:
Hello dear. So raloxifene is less effective as compared to tamoxifen or anastrazole/letrozole for the prevention. As per guidelines , we dont offer raloxifene to our patients.
Thanks and regards
Hello. raloxifene(evista) is less effective
Detailed Answer:
Hello dear. So raloxifene is less effective as compared to tamoxifen or anastrazole/letrozole for the prevention. As per guidelines , we dont offer raloxifene to our patients.
Thanks and regards
Note: For further queries related to kidney problems Click here.
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
